In her rookie LPGA Tour season of 2019, Lee struck the jackpot with a two-stroke victory in the U.S Women's Open, the event where she had tied for fifth on her major debut two years earlier. She also came joint sixth in the ANA Inspiration and tied ninth in the AIG Women’s Open at Woburn that year.
By then she had become known as Jeongeun Lee6 to tell her apart from other Korean golfers with the same name. She hit the headlines again in 2021 with a 10-under-par 61 at the Evian Championship. It set the lowest round ever recorded in a major, male or female, but was matched two days later by Leona Maguire.
Five ahead with a round to play, however, Lee6 was caught by Minjee Lee, who shot 64 to come from seven back, and it was the Australian who took the title at the first extra hole.